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Absence of B Cells in Brainstem and White Matter Lesions Associates With Less Severe Disease and Absence of Oligoclonal Bands in MS

OBJECTIVE: To determine whether B-cell presence in brainstem and white matter (WM) lesions is associated with poorer pathological and clinical characteristics in advanced MS autopsy cases. METHODS: Autopsy tissue of 140 MS and 24 control cases and biopsy tissue of 24 patients with MS were examined f...

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Detalhes bibliográficos
Publicado no:Neurol Neuroimmunol Neuroinflamm
Main Authors: Fransen, Nina L., de Jong, Brigit A., Heß, Katharina, Kuhlmann, Tanja, Vincenten, Maria C.J., Hamann, Jörg, Huitinga, Inge, Smolders, Joost
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862088/
https://ncbi.nlm.nih.gov/pubmed/33504635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000955
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