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Globally defining the effects of mutations in a picornavirus capsid

The capsids of non-enveloped viruses are highly multimeric and multifunctional protein assemblies that play key roles in viral biology and pathogenesis. Despite their importance, a comprehensive understanding of how mutations affect viral fitness across different structural and functional attributes...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Mattenberger, Florian, Latorre, Victor, Tirosh, Omer, Stern, Adi, Geller, Ron
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7861617/
https://ncbi.nlm.nih.gov/pubmed/33432927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64256
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