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A Metabolic Bottleneck for Stem Cell Transformation
Although oncogenic mutations predispose tissue stem cells to tumor initiation, the rate-limiting processes for stem cell immortalization remain unknown. In this issue of Cell, Bonnay et al. identify enhanced electron transport chain activity as a critical determinant of this process, establishing me...
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| Publicat a: | Cell |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7861329/ https://ncbi.nlm.nih.gov/pubmed/32946778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.08.038 |
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