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Allergen-specific IgG(+) memory B cells are temporally linked to IgE memory responses

BACKGROUND: IgE is the least abundant immunoglobulin and tightly regulated, and IgE-producing B cells are rare. The cellular origin and evolution of IgE responses are poorly understood. OBJECTIVE: The cellular and clonal origin of IgE memory responses following mucosal allergen exposure by sublingua...

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Détails bibliographiques
Publié dans:J Allergy Clin Immunol
Auteurs principaux: Hoof, Ilka, Schulten, Veronique, Layhadi, Janice A., Stranzl, Thomas, Christensen, Lars H., Herrera de la Mata, Sara, Seumois, Grégory, Vijayanand, Pandurangan, Lundegaard, Claus, Niss, Kristoffer, Lund, Anders, Ahrenfeldt, Johanne, Holm, Jens, Steveling, Esther, Sharif, Hanisah, Durham, Stephen R., Peters, Björn, Shamji, Mohamed H., Andersen, Peter S.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860973/
https://ncbi.nlm.nih.gov/pubmed/31883847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.11.046
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