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The BTLA and PD‐1 signaling pathways independently regulate the proliferation and cytotoxicity of human peripheral blood γδ T cells

BACKGROUND: B‐ and T‐lymphocyte attenuator (BTLA) and programmed cell death‐1 (PD‐1) inhibit γδ T cell homeostasis and activation. This study aimed to determine whether BTLA and PD‐1 signaling pathways were convergent or independent in human peripheral blood γδ T cells. Herein we demonstrate that th...

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Dettagli Bibliografici
Pubblicato in:Immun Inflamm Dis
Autori principali: Hwang, Hyun J., Lee, Jae J., Kang, Sung H., Suh, Jin K., Choi, Eun S., Jang, Seongsoo, Hwang, Sang‐Hyun, Koh, Kyung‐Nam, Im, Ho J., Kim, Nayoung
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860523/
https://ncbi.nlm.nih.gov/pubmed/33332777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.390
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