Changes in epigenetic profiles throughout early childhood and their relationship to the response to pneumococcal vaccination

BACKGROUND: Pneumococcal infections are a major cause of morbidity and mortality in young children and immaturity of the immune system partly underlies poor vaccine responses seen in the young. Emerging evidence suggests a key role for epigenetics in the maturation and regulation of the immune syste...

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Vydáno v:Clin Epigenetics
Hlavní autoři: Pischedda, Sara, O’Connor, Daniel, Fairfax, Benjamin P., Salas, Antonio, Martinon-Torres, Federico, Pollard, Andrew J., Trück, Johannes
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860179/
https://ncbi.nlm.nih.gov/pubmed/33541404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01012-w
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