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Chronic Exposure to Methylmercury Enhances the Anorexigenic Effects of Leptin in C57BL/6J Male Mice

Several studies have demonstrated that heavy metals disrupt energy homeostasis. Leptin inhibits food intake and decreases body weight through activation of its receptor in the hypothalamus. The impact of heavy metals on leptin signaling in the hypothalamus is unclear. Here, we show that the environm...

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Detalhes bibliográficos
Publicado no:Food Chem Toxicol
Main Authors: Ferrer, Beatriz, Prince, Lisa M, Tinkov, Alexey A, Santamaria, Abel, Farina, Marcelo, Rocha, João Batista, Bowman, Aaron B, Aschner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860169/
https://ncbi.nlm.nih.gov/pubmed/33338554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2020.111924
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