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Hydrostatic pressure prevents chondrocyte differentiation through heterochromatin remodeling

Articular cartilage protects and lubricates joints for smooth motion and transmission of loads. Owing to its high water content, chondrocytes within the cartilage are exposed to high levels of hydrostatic pressure, which has been shown to promote chondrocyte identity through unknown mechanisms. Here...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Maki, Koichiro, Nava, Michele M., Villeneuve, Clémentine, Chang, Minki, Furukawa, Katsuko S., Ushida, Takashi, Wickström, Sara A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860130/
https://ncbi.nlm.nih.gov/pubmed/33310912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.247643
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