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Daam2 couples translocation and clustering of Wnt receptor signalosomes through Rac1

Wnt signaling plays a critical role in development across species and is dysregulated in a host of human diseases. A key step in signal transduction is the formation of Wnt receptor signalosomes, during which a large number of components translocate to the membrane, cluster together and amplify down...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Cristobal, Carlo D., Ye, Qi, Jo, Juyeon, Ding, Xiaoyun, Wang, Chih-Yen, Cortes, Diego, Chen, Zheng, Lee, Hyun Kyoung
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860116/
https://ncbi.nlm.nih.gov/pubmed/33310913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.251140
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