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Obesity reduces the anticancer effect of AdipoRon against orthotopic pancreatic cancer in diet-induced obese mice

The antidiabetic adiponectin receptor agonist AdipoRon has been shown to suppress the tumour growth of human pancreatic cancer cells. Because obesity and diabetes affect pancreatic cancer progression and chemoresistance, we investigated the effect of AdipoRon on orthotopic tumour growth of Panc02 pa...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Takenaga, Keizo, Akimoto, Miho, Koshikawa, Nobuko, Nagase, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859201/
https://ncbi.nlm.nih.gov/pubmed/33536560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82617-2
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