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The Experimental TASK-1 Potassium Channel Inhibitor A293 Can Be Employed for Rhythm Control of Persistent Atrial Fibrillation in a Translational Large Animal Model
BACKGROUND: Upregulation of the two-pore-domain potassium channel TASK-1 (hK(2)(P)3.1) was recently described in patients suffering from atrial fibrillation (AF) and resulted in shortening of the atrial action potential. In the human heart, TASK-1 channels facilitate repolarization and are specifica...
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| Pubblicato in: | Front Physiol |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7858671/ https://ncbi.nlm.nih.gov/pubmed/33551849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.629421 |
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