Feasibility of ex vivo fluorescence imaging of angiogenesis in (non-) culprit human carotid atherosclerotic plaques using bevacizumab-800CW

Vascular endothelial growth factor-A (VEGF-A) is assumed to play a crucial role in the development and rupture of vulnerable plaques in the atherosclerotic process. We used a VEGF-A targeted fluorescent antibody (bevacizumab-IRDye800CW [bevacizumab-800CW]) to image and visualize the distribution of...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Huisman, Lydian A., Steinkamp, Pieter J., Hillebrands, Jan-Luuk, Zeebregts, Clark J., Linssen, Matthijs D., Jorritsma-Smit, Annelies, Slart, Riemer H. J. A., van Dam, Gooitzen M., Boersma, Hendrikus H.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7858611/
https://ncbi.nlm.nih.gov/pubmed/33536498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82568-8
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