B-cells expressing NgR1 and NgR3 are localized to EAE-induced inflammatory infiltrates and are stimulated by BAFF

We have previously reported evidence that Nogo-A activation of Nogo-receptor 1 (NgR1) can drive axonal dystrophy during the neurological progression of experimental autoimmune encephalomyelitis (EAE). However, the B-cell activating factor (BAFF/BlyS) may also be an important ligand of NgR during neu...

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Pubblicato in:Sci Rep
Autori principali: Bakhuraysah, Maha M., Theotokis, Paschalis, Lee, Jae Young, Alrehaili, Amani A., Aui, Pei-Mun, Figgett, William A., Azari, Michael F., Abou-Afech, John-Paul, Mackay, Fabienne, Siatskas, Christopher, Alderuccio, Frank, Strittmatter, Stephen M., Grigoriadis, Nikolaos, Petratos, Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7858582/
https://ncbi.nlm.nih.gov/pubmed/33536561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82346-6
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