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A Trap-Door Mechanism for Zinc Acquisition by Streptococcus pneumoniae AdcA

Zinc is an essential element in all domains of life. Nonetheless, how prokaryotes achieve selective acquisition of zinc from the extracellular environment remains poorly understood. Here, we elucidate a novel mechanism for zinc-binding in AdcA, a solute-binding protein of Streptococcus pneumoniae. C...

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Veröffentlicht in:mBio
Hauptverfasser: Luo, Zhenyao, Morey, Jacqueline R., Deplazes, Evelyne, Motygullina, Alina, Tan, Aimee, Ganio, Katherine, Neville, Stephanie L., Eleftheriadis, Nikolaos, Isselstein, Michael, Pederick, Victoria G., Paton, James C., Cordes, Thorben, Harmer, Jeffrey R., Kobe, Bostjan, McDevitt, Christopher A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7858048/
https://ncbi.nlm.nih.gov/pubmed/33531394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01958-20
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