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Effect of linagliptin versus placebo on cardiovascular and kidney outcomes in nephrotic-range proteinuria and type 2 diabetes: the CARMELINA randomized controlled trial

BACKGROUND: Nephrotic-range proteinuria (NRP) is associated with rapid kidney function loss and increased cardiovascular (CV) disease risk. We assessed the effects of linagliptin (LINA) on CV and kidney outcomes in people with Type 2 diabetes (T2D) with or without NRP. METHODS: Cardiovascular and re...

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Vydáno v:Clin Kidney J
Hlavní autoři: Wanner, Christoph, Cooper, Mark E, Johansen, Odd Erik, Toto, Robert, Rosenstock, Julio, McGuire, Darren K, Kahn, Steven E, Pfarr, Egon, Schnaidt, Sven, von Eynatten, Maximilian, George, Jyothis T, Gollop, Nicholas D, Marx, Nikolaus, Alexander, John H, Zinman, Bernard, Perkovic, Vlado
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857804/
https://ncbi.nlm.nih.gov/pubmed/33564423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ckj/sfaa225
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