DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics

The spatiotemporal proteome of the intervertebral disc (IVD) underpins its integrity and function. We present DIPPER, a deep and comprehensive IVD proteomic resource comprising 94 genome-wide profiles from 17 individuals. To begin with, protein modules defining key directional trends spanning the la...

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Vydáno v:eLife
Hlavní autoři: Tam, Vivian, Chen, Peikai, Yee, Anita, Solis, Nestor, Klein, Theo, Kudelko, Mateusz, Sharma, Rakesh, Chan, Wilson CW, Overall, Christopher M, Haglund, Lisbet, Sham, Pak C, Cheah, Kathryn Song Eng, Chan, Danny
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2020
Témata:
Computational and Systems Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857729/
https://ncbi.nlm.nih.gov/pubmed/33382035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64940
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