Noninvasive imaging and quantification of bile salt hydrolase activity: From bacteria to humans

The microbiome-produced enzyme bile salt hydrolase (BSH) plays a central role in human health, but its function remains unclear due to the lack of suitable methods for measuring its activity. Here, we have developed a novel optical tool based on ultrasensitive bioluminescent imaging and demonstrated...

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Pubblicato in:Sci Adv
Autori principali: Khodakivskyi, Pavlo V., Lauber, Christian L., Yevtodiyenko, Aleksey, Bazhin, Arkadiy A., Bruce, Stephen, Ringel-Kulka, Tamar, Ringel, Yehuda, Bétrisey, Bertrand, Torres, Joana, Hu, Jianzhong, Chou, Chieh Jason, Goun, Elena A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2021
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857686/
https://ncbi.nlm.nih.gov/pubmed/33536224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz9857
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