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Transmembrane signaling and cytoplasmic signal conversion by dimeric transmembrane helix 2 and a linker domain of the DcuS sensor kinase

Transmembrane (TM) signaling is a key process of membrane-bound sensor kinases. The C(4)-dicarboxylate (fumarate) responsive sensor kinase DcuS of Escherichia coli is anchored by TM helices TM1 and TM2 in the membrane. Signal transmission across the membrane relies on the piston-type movement of the...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Stopp, Marius, Steinmetz, Philipp Aloysius, Schubert, Christopher, Griesinger, Christian, Schneider, Dirk, Unden, Gottfried
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857512/
https://ncbi.nlm.nih.gov/pubmed/33277358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015999
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