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Retinoblastoma protein promotes uterine epithelial cell cycle arrest and necroptosis for embryo invasion

Retinoblastoma protein (RB) encoded by Rb1 is a prominent inducer of cell cycle arrest (CCA). The hormone progesterone (P(4)) promotes CCA in the uterine epithelium and previous studies indicated that P(4) activates RB by reducing the phosphorylated, inactive form of RB. Here, we show that embryo im...

詳細記述

保存先:
書誌詳細
出版年:EMBO Rep
主要な著者: Akaeda, Shun, Hirota, Yasushi, Fukui, Yamato, Aikawa, Shizu, Shimizu‐Hirota, Ryoko, Kaku, Tetsuaki, Gebril, Mona, Hirata, Tomoyuki, Hiraoka, Takehiro, Matsuo, Mitsunori, Haraguchi, Hirofumi, Saito‐Kanatani, Mayuko, Takeda, Norihiko, Fujii, Tomoyuki, Osuga, Yutaka
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857437/
https://ncbi.nlm.nih.gov/pubmed/33399260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050927
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