Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion

Autotaxin (ATX) is a prometastatic enzyme initially isolated from the conditioned medium of human melanoma cells that stimulates a myriad of biological activities, including angiogenesis and the promotion of cell growth, survival, and differentiation through the production of lysophosphatidic acid (...

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Foilsithe in:Mol Cancer Ther
Main Authors: Saunders, Lauren P., Ouellette, Amy, Bandle, Russ, Chang, William Chozen, Zhou, Hongwen, Misra, Raj N., De La Cruz, Enrique M., Braddock, Demetrios T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857123/
https://ncbi.nlm.nih.gov/pubmed/18852138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0463
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