Effect of CYP2D6 polymorphisms on plasma concentration and therapeutic effect of risperidone

BACKGROUND: This study aimed to investigate the influence of CYP2D6 polymorphisms on risperidone plasma concentrations in patients with schizophrenia. Based on pharmacogenomics, we examined whether plasma concentration of risperidone is associated with clinical response and adverse side-effects. MET...

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Detalhes bibliográficos
Publicado no:BMC Psychiatry
Main Authors: Lu, Jinjun, Yang, Ye, Lu, Jian, Wang, Zuqing, He, Yiping, Yan, Yeliang, Fu, Kai, Jiang, Wenjuan, Xu, Yunqing, Wu, Renrong, Liu, Wenqing, Zhao, Jingping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856706/
https://ncbi.nlm.nih.gov/pubmed/33535976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12888-020-03034-9
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