PALB2 upregulation is associated with a poor prognosis in pancreatic ductal adenocarcinoma

During DNA repair, BRCA1 and BRCA2 interact with the tumor suppressor partner and localizer of BRCA2 (PALB2). PALB2 mutations are associated with an increased risk of breast and ovarian carcinoma, and upregulated PALB2 expression is associated with poor clinical outcomes. The present study investiga...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Ge, Ouyang, Huang, Anle, Wang, Xin, Chen, Yuling, Ye, Yuanchun, Schomburg, Lutz
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2021
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856690/
https://ncbi.nlm.nih.gov/pubmed/33613713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12485
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