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Ultra-High Dose-Rate, Pulsed (FLASH) Radiotherapy with Carbon Ions: Generation of Early, Transient, Highly Oxygenated Conditions in the Tumor Environment

It is well known that molecular oxygen is a product of the radiolysis of water with high-linear energy transfer (LET) radiation, which is distinct from low-LET radiation wherein O(2) radiolytic yield is negligible. Since O(2) is a powerful radiosensitizer, this fact is of practical relevance in canc...

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Detalhes bibliográficos
Publicado no:Radiat Res
Main Authors: Zakaria, Abdullah Muhammad, Colangelo, Nicholas W., Meesungnoen, Jintana, Azzam, Edouard I., Plourde, Marc-Émile, Jay-Gerin, Jean-Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856087/
https://ncbi.nlm.nih.gov/pubmed/32853343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RADE-19-00015.1
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