Loss of ClC-6 Affects Vascular Smooth Muscle Contractility and Arterial Stiffness Via Alterations to Golgi Calcium Stores

Genome-wide association studies (GWAS) have found a number of potential genes involved in blood pressure regulation; however, the functional role of many of these candidates has yet to be established. One such candidate gene is CLCN6, which encodes the transmembrane protein, ClC-6. Although the CLCN...

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Publicado no:Hypertension
Main Authors: Klemens, Christine A., Chulkov, Evgeny G., Wu, Jing, Khan, Md Abdul Hye, Levchenko, Vladislav, Flister, Michael J., Imig, John D., Kriegel, Alison J., Palygin, Oleg, Staruschenko, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856014/
https://ncbi.nlm.nih.gov/pubmed/33390052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.120.16589
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