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Mice lacking substance P have normal bone modeling but diminished bone formation, increased resorption, and accelerated osteopenia with aging

Substance P (SP) is a sensory neuropeptide that is expressed by the neurons innervating bone. There is considerable evidence that SP can regulate bone cell function in vitro, but it is unclear whether SP modulates bone modeling or remodeling in vivo. To answer this question we characterized the bone...

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Bibliografski detalji
Izdano u:Bone
Glavni autori: Wang, Liping, Hou, Saiyun, Sabsovich, Ilya, Guo, Tian-Zhi, Wei, Tzuping, Kingery, Wade S.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856000/
https://ncbi.nlm.nih.gov/pubmed/33333245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2020.115806
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