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Exploration of bacterial bottlenecks and Streptococcus pneumoniae pathogenesis by CRISPRi-seq
Streptococcus pneumoniae is an opportunistic human pathogen that causes invasive disease, including pneumonia, with greater health risks upon influenza A virus (IAV) co-infection. To facilitate pathogenesis studies in vivo, we developed an inducible CRISPR interference system (CRISPRi-seq) that enab...
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| Vydáno v: | Cell Host Microbe |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7855995/ https://ncbi.nlm.nih.gov/pubmed/33120116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.10.001 |
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