Rho-Kinase 1/2 Inhibition Prevents Transforming Growth Factor-β-Induced Effects on Pulmonary Remodeling and Repair

Transforming growth factor (TGF)-β-induced myofibroblast transformation and alterations in mesenchymal-epithelial interactions contribute to chronic lung diseases such as chronic obstructive pulmonary disease (COPD), asthma and pulmonary fibrosis. Rho-associated coiled-coil-forming protein kinase (R...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Pharmacol
Prif Awduron: Wu, Xinhui, Verschut, Vicky, Woest, Manon E., Ng-Blichfeldt, John-Poul, Matias, Ana, Villetti, Gino, Accetta, Alessandro, Facchinetti, Fabrizio, Gosens, Reinoud, Kistemaker, Loes E. M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2021
Pynciau:
Pharmacology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855981/
https://ncbi.nlm.nih.gov/pubmed/33551810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.609509
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