Deletion of growth hormone receptor in hypothalamic neurons affects the adaptation capacity to aerobic exercise

The hypothalamus mediates important exercise-induced metabolic adaptations, possibly via hormonal signals. Hypothalamic leptin receptor (LepR)- and steroidogenic factor 1 (SF1)-expressing neurons are directly responsive to growth hormone (GH) and deletion of GH receptor (GHR) in these cells impairs...

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Pubblicato in:Peptides
Autori principali: Pedroso, João A.B., dos Santos, Lucas B.P., Furigo, Isadora C., Spagnol, Alexandre R., Wasinski, Frederick, List, Edward O., Kopchick, John J., Donato, Jose
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855886/
https://ncbi.nlm.nih.gov/pubmed/33069692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2020.170426
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