Global and site-specific effect of phosphorylation on protein turnover

To date, the effects of specific modification types and sites on protein lifetime have not been systematically illustrated. Here, we describe a proteomic method, DeltaSILAC, to quantitatively assess the impact of site-specific phosphorylation on the turnover of thousands of proteins in live cells. B...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Wu, Chongde, Ba, Qian, Lu, Dayun, Li, Wenxue, Salovska, Barbora, Hou, Pingfu, Mueller, Torsten, Rosenberger, George, Gao, Erli, Di, Yi, Zhou, Hu, Fornasiero, Eugenio F., Liu, Yansheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855865/
https://ncbi.nlm.nih.gov/pubmed/33238149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.10.025
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