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TET2 chemically modifies tRNAs and regulates tRNA fragment levels
The Ten-eleven Translocation 2 (TET2) protein, which oxidizes 5-methylcytosine in DNA, can also bind RNA; however, the targets and function of TET2–RNA interactions in vivo are not fully understood. Using stringent affinity tags introduced at the Tet2 locus, we purified and sequenced TET2-crosslinke...
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| Gepubliceerd in: | Nat Struct Mol Biol |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7855721/ https://ncbi.nlm.nih.gov/pubmed/33230319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-00526-w |
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