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Synergistic Interplay of Covalent and Non-Covalent Interactions in Reactive Polymer Nanoassembly Facilitates Intracellular Delivery of Antibodies
Utility of antibody as a therapeutic is by far limited to extracellular or membrane bound proteins, even though these molecules can be engineered to recognize many “undruggable” therapeutic targets. The primary impediments in developing large antibodies as drugs against intracellular targets involve...
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| Udgivet i: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7855684/ https://ncbi.nlm.nih.gov/pubmed/33034131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202010412 |
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