Synergistic activity of phage PEV20-ciprofloxacin combination powder formulation—A proof-of-principle study in a P. aeruginosa lung infection model

Combination treatment using bacteriophage and antibiotics is potentially an advanced approach to combatting antimicrobial-resistant bacterial infections. We have recently developed an inhalable powder by co-spray drying Pseudomonas phage PEV20 with ciprofloxacin. The purpose of this study was to ass...

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Veröffentlicht in:Eur J Pharm Biopharm
Hauptverfasser: Lin, Yu, Quan, Diana, Chang, Rachel Yoon Kyung, Chow, Michael Y. T., Wang, Yuncheng, Li, Mengyu, Morales, Sandra, Britton, Warwick J, Kutter, Elizabeth, Li, Jian, Chan, Hak-Kim
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855557/
https://ncbi.nlm.nih.gov/pubmed/33253892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2020.11.019
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