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Cortical thickness mediates the relationship between DRD2 C957T polymorphism and executive function across the adult lifespan

Dopamine (DA) signaling is critical for optimal cognitive performance. Aging is accompanied by a change in the strength of this signaling, with a loss of striatal and extrastriatal D2 binding potential. The reduction in dopamine modulation with age negatively influences various aspects of cognition....

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Bibliografische gegevens
Gepubliceerd in:Brain Struct Funct
Hoofdauteurs: Miranda, Giuseppe G., Rodrigue, Karen M., Kennedy, Kristen M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855542/
https://ncbi.nlm.nih.gov/pubmed/33179159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-020-02169-5
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