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Inhibition of CDK2/CyclinE1 by xanthones from the mangosteen (Garcinia mangostana): A structure-activity relationship study

Uncontrolled regulation of cyclin dependent kinases (CDKs) has negative implications in many cancers and malignancies and has recently led to the approval of select CDK inhibitors. Herein we present data reporting that xanthones, a class of compounds isolated from the purple mangosteen (Garcinia man...

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Publicat a:Nat Prod Res
Autors principals: Nauman, Mirielle C., Tocmo, Restituto, Vemu, Bhaskar, Veenstra, Jacob P., Johnson, Jeremy J.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854934/
https://ncbi.nlm.nih.gov/pubmed/32691623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14786419.2020.1777413
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