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Classification of T-cell activation via autofluorescence lifetime imaging

The function of a T cell depends on its subtype and activation state. Here, we show that the imaging of autofluorescence-lifetime signals from quiescent and activated T cells can be used to classify the cells. T cells isolated from human peripheral blood and activated in culture via a tetrameric ant...

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Detalles Bibliográficos
Publicado en:Nat Biomed Eng
Main Authors: Walsh, Alex J., Mueller, Katie, Tweed, Kelsey, Jones, Isabel, Walsh, Christine M., Piscopo, Nicole, Niemi, Natalie M., Pagliarini, David J., Saha, Krishanu, Skala, Melissa C.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854821/
https://ncbi.nlm.nih.gov/pubmed/32719514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-020-0592-z
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