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TGFβ signalling acts as a molecular brake of myoblast fusion

Fusion of nascent myoblasts to pre-existing myofibres is critical for skeletal muscle growth and repair. The vast majority of molecules known to regulate myoblast fusion are necessary in this process. Here, we uncover, through high-throughput in vitro assays and in vivo studies in the chicken embryo...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Melendez, Julie, Sieiro, Daniel, Salgado, David, Morin, Valérie, Dejardin, Marie-Julie, Zhou, Chan, Mullen, Alan C., Marcelle, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854724/
https://ncbi.nlm.nih.gov/pubmed/33531476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20290-1
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