Nalaganje...
A Proposed Concept for Defective Mitophagy Leading to Late Stage Ineffective Erythropoiesis in Pyruvate Kinase Deficiency
Pyruvate kinase deficiency (PKD) is a rare congenital hemolytic anemia caused by mutations in the PKLR gene. Here, we review pathophysiological aspects of PKD, focusing on the interplay between pyruvate kinase (PK)-activity and reticulocyte maturation in the light of ferroptosis, an iron-dependent p...
Shranjeno v:
| izdano v: | Front Physiol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2021
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7854701/ https://ncbi.nlm.nih.gov/pubmed/33551834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.609103 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|