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A practical solution to pseudoreplication bias in single-cell studies

Cells from the same individual share common genetic and environmental backgrounds and are not statistically independent; therefore, they are subsamples or pseudoreplicates. Thus, single-cell data have a hierarchical structure that many current single-cell methods do not address, leading to biased in...

詳細記述

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書誌詳細
出版年:Nat Commun
主要な著者: Zimmerman, Kip D., Espeland, Mark A., Langefeld, Carl D.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854630/
https://ncbi.nlm.nih.gov/pubmed/33531494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21038-1
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