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Strand-specific Single-stranded DNA Sequencing (4S-seq) of E. coli genomes

Most bacterial genomes have biased nucleotide composition, and the asymmetry is considered to be caused by a single-stranded DNA (ssDNA) deamination arising from the bacterial replication machinery. In order to evaluate the relationship experimentally, the position and frequency of ssDNA formed duri...

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Detalles Bibliográficos
Publicado en:Bio Protoc
Main Authors: Masuda, Takahiro, Kono, Nobuaki, Tomita, Masaru, Arakawa, Kazuharu
Formato: Artigo
Idioma:Inglês
Publicado: Bio-Protocol 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854271/
https://ncbi.nlm.nih.gov/pubmed/33654836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3329
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