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Detection of Heteroplasmic Variants in the Mitochondrial Genome through Massive Parallel Sequencing
Detecting heteroplasmies in the mitochondrial DNA (mtDNA) has been a challenge for many years. In the past, Sanger sequencing was the main option to perform this analysis, however, this method could not detect low frequency heteroplasmies. Massive Parallel Sequencing (MPS) provides the opportunity t...
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| 發表在: | Bio Protoc |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Bio-Protocol
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7854219/ https://ncbi.nlm.nih.gov/pubmed/33654798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3283 |
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