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Tapentadol for the Treatment of Moderate-to-Severe Acute Pain in Children Under the Age of Two Years

BACKGROUND: Pharmacokinetics (PK), efficacy, and safety of the opioid analgesic tapentadol in the treatment of moderate-to-severe acute pain have so far not been investigated in pediatric patients <2 years of age. PATIENTS AND METHODS: Two multicenter, open-label trials assessed the pharmacokinet...

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Pubblicato in:J Pain Res
Autori principali: Eissa, Ayman, Tarau, Eva, Beuter, Christoph, Radic, Tatjana, Watson, Estelle, Sohns, Melanie, Lefeber, Claudia, Hammer, Gregory B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7853441/
https://ncbi.nlm.nih.gov/pubmed/33542653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S269530
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