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Recombinant human parathyroid hormone (1–84) is effective in CASR-associated hypoparathyroidism

INTRODUCTION: Gain-of-function mutations in the CASR gene cause Autosomal Dominant Hypocalcemia Type 1 (ADH1), the most common genetic cause of isolated hypoparathyroidism. Subjects have increased calcium sensitivity in the renal tubule, leading to increased urinary calcium excretion, nephrocalcinos...

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Publicado en:Eur J Endocrinol
Autores principales: Hawkes, Colin Patrick, Shulman, Dorothy I, Levine, Michael A
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7853300/
https://ncbi.nlm.nih.gov/pubmed/33112267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EJE-20-0710
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