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Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer

Ovarian cancer is the most lethal malignant tumor of female reproductive system. It is well-known that induction of STING-mediated type I interferons can enhance the resultant antitumor activity. However, STING pathway is usually inactivated in cancer cells at multiple levels. Here, we identified de...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Differ
Hauptverfasser: Zhang, Jiawen, Chen, Yunfei, Chen, Xianfei, Zhang, Wen, Zhao, Linlin, Weng, Linjun, Tian, Hongling, Wu, Zhiqiang, Tan, Xiao, Ge, Xin, Wang, Ping, Fang, Lan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7853139/
https://ncbi.nlm.nih.gov/pubmed/32678307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0588-y
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