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Inbred lab mice are not isogenic: genetic variation within inbred strains used to infer the mutation rate per nucleotide site

For over a century, inbred mice have been used in many areas of genetics research to gain insight into the genetic variation underlying traits of interest. The generalizability of any genetic research study in inbred mice is dependent upon all individual mice being genetically identical, which in tu...

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Detalhes bibliográficos
Publicado no:Heredity (Edinb)
Main Authors: Chebib, Jobran, Jackson, Benjamin C., López-Cortegano, Eugenio, Tautz, Diethard, Keightley, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852876/
https://ncbi.nlm.nih.gov/pubmed/32868871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41437-020-00361-1
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