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Inbred lab mice are not isogenic: genetic variation within inbred strains used to infer the mutation rate per nucleotide site
For over a century, inbred mice have been used in many areas of genetics research to gain insight into the genetic variation underlying traits of interest. The generalizability of any genetic research study in inbred mice is dependent upon all individual mice being genetically identical, which in tu...
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| Publicado no: | Heredity (Edinb) |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7852876/ https://ncbi.nlm.nih.gov/pubmed/32868871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41437-020-00361-1 |
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