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CaMKIIα-driven, phosphatase-checked postsynaptic plasticity via phase separation

Ca(2+)/calmodulin-dependent kinase IIα (CaMKIIα) is essential for synaptic plasticity and learning by decoding synaptic Ca(2+) oscillations. Despite decades of extensive research, new mechanisms underlying CaMKIIα’s function in synapses are still being discovered. Here, we discover that Shank3 is a...

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Detalles Bibliográficos
Publicado en:Cell Res
Main Authors: Cai, Qixu, Zeng, Menglong, Wu, Xiandeng, Wu, Haowei, Zhan, Yumeng, Tian, Ruijun, Zhang, Mingjie
Formato: Artigo
Idioma:Inglês
Publicado: Springer Singapore 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852677/
https://ncbi.nlm.nih.gov/pubmed/33235361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-020-00439-9
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