Cell fate determined by the activation balance between PKR and SPHK1

Double-stranded RNA (dsRNA)-dependent protein kinase R (PKR) activation via autophosphorylation is the central cellular response to stress that promotes cell death or apoptosis. However, the key factors and mechanisms behind the simultaneous activation of pro-survival signaling pathways remain unkno...

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Bibliografiske detaljer
Udgivet i:Cell Death Differ
Main Authors: Qiao, Han, Jiang, Tianqing, Mu, Peiqiang, Chen, Xiaoxuan, Wen, Xianhui, Hu, Zhangsheng, Tang, Shulin, Wen, Jikai, Deng, Yiqun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852545/
https://ncbi.nlm.nih.gov/pubmed/32801355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00608-8
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