Cartilage-like composition of keloid scar extracellular matrix suggests fibroblast mis-differentiation in disease

Following wound damage to the skin, the scarring spectrum is wide-ranging, from a manageable normal scar through to pathological keloids. The question remains whether these fibrotic lesions represent simply a quantitative extreme, or alternatively, whether they are qualitatively distinct. A three-wa...

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Veröffentlicht in:Matrix Biol Plus
Hauptverfasser: Barallobre-Barreiro, Javier, Woods, Elizabeth, Bell, Rachel E., Easton, Jennifer A., Hobbs, Carl, Eager, Michael, Baig, Ferheen, Ross, Alastair Mackenzie, Mallipeddi, Raj, Powell, Barry, Soldin, Mark, Mayr, Manuel, Shaw, Tanya J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852214/
https://ncbi.nlm.nih.gov/pubmed/33543013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mbplus.2019.100016
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