Comparative genomics and transcriptomics analyses provide insights into the high yield and regulatory mechanism of Norvancomycin biosynthesis in Amycolatopsis orientalis NCPC 2-48

BACKGROUND: Norvancomycin has been widely used in clinic to treat against MRSA (Methicillin-resistant Staphylococcus aureus) and MRSE (Methicillin-resistant Staphylococcus epidermidis) infections in China. Amycolatopsis orientalis NCPC 2-48, a high yield strain derived from A. orientalis CPCC 200066...

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Veröffentlicht in:Microb Cell Fact
Hauptverfasser: Li, Xingxing, Zhang, Cong, Zhao, Ying, Lei, Xuan, Jiang, Zhibo, Zhang, Xuexia, Zheng, Zhihui, Si, Shuyi, Wang, Lifei, Hong, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852140/
https://ncbi.nlm.nih.gov/pubmed/33531006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-021-01521-6
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