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Nonmuscle myosin-2 contractility-dependent actin turnover limits the length of epithelial microvilli

Brush border microvilli enable functions that are critical for epithelial homeostasis, including solute uptake and host defense. However, the mechanisms that regulate the assembly and morphology of these protrusions are poorly understood. The parallel actin bundles that support microvilli have their...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Chinowsky, Colbie R., Pinette, Julia A., Meenderink, Leslie M., Lau, Ken S., Tyska, Matthew J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851865/
https://ncbi.nlm.nih.gov/pubmed/33026933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-09-0582
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