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Genetic Polymorphism Effect on Warfarin–Rifampin Interaction: A Case Report and Review of Literature
Warfarin–rifampin interaction has been reported since the 1970s. Due to rifampin’s strong induction of CYP2C9, most cases could not attain the target international normalized ratio (INR) despite warfarin dose escalation. Genetic polymorphisms determine up to 50% of warfarin dose variability. A 38-ye...
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| Publicado no: | Pharmgenomics Pers Med |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7851577/ https://ncbi.nlm.nih.gov/pubmed/33542643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S288918 |
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